Commander of the Specialist Operations Unit, Hayato Kirijo is so intimidating that a look from him could silence a crying child. It is this man who has been tasked with the job of a home tutor for a young girl, Rise, whose veins run with the blood of the living weapons, the Chimeramix. Kirijo had doubts about his mission, but once he finds out that there are people who are out to harm Rise so that she realizes her purpose as a weapon...?!